Seed: Microscopy and the Art of Sudoku
http://www.seedmagazine.com/news/2006/03/microscopy_and_the_art_of_sudo.php
"When Cornell physicist Veit Elser attempted to demystify an esoteric imaging problem for biologists, he had no idea his solution would also help subway riders and break room loiterers around the world figure out those challenging, Sudoku puzzles."